Tissue plasminogen activator-like protease
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United States of America Patent
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Issued Date -
Nov 7, 2002
app pub date -
Mar 22, 2002
filing date -
May 28, 1997
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Abstract
The present invention relates to a novel t-PALP protein which is a member of the serine protease family. In particular, isolated nucleic acid molecules are provided encoding the human t-PALP protein. t-PALP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of t-PALP activity. Also provided are diagnostic methods for detecting circulatory system-related disorders and therapeutic methods for treating circulatory system-related disorders.
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