Method and compositions for the treatment or amelioration of female sexual dysfunction

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20020165122A1
SERIAL NO

10136387

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provide a method of treating sexual dysfunction in a female, including the vasculogenic symptoms of delayed vaginal engorgement, diminished vaginal lubrication, pain or discomfort with intercourse (dyspareunia), diminished vaginal sensation, diminished vaginal orgasm, diminished clitoral sensation or diminished clitoral orgasm, or of combating vaginal pain by stimulating peripheral pelvic nerve release of nitric oxide (NO). The method comprises administering to a female in need of such treatment a therapeutically effective amount of a compound which acts on a mid-brain pathway to increase blood flow to the ilio-hypogastric-pudendal artery bed and stimulate the release of nitric oxide (NO) from peripheral NANC nerve cells. The preferred compound for the method of this invention is apomorphine or one of its pharmaceutically acceptable salts, esters, or pro-drugs.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
QUEEN'S UNIVERSITY AT KINGSTONKINGSTON ONTARIO108

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adams, Michael A Kingston, CA 45 448
Heaton, Jeremy P W Kingston, CA 25 317

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 4801587 Impotence ointment 125 1987
 
QUEEN'S UNIVERSITY AT KINGSTON (1)
* 5770606 Dosage forms and method for ameliorating male erectile dysfunction 46 1995
 
Pentech Pharmaceuticals, Inc. (1)
* 5945117 Treatment of female sexual dysfunction 36 1998
 
NORTHWESTERN UNIVERSITY (2)
* 4543256 (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers 19 1982
* 4687773 (+)-N-N-propylnorapomorphine and selective limbic activity 15 1985
 
PFIZER INC. (1)
* 5270323 Method of treating impotence 59 1993
 
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (1)
* 4727064 Pharmaceutical preparations containing cyclodextrin derivatives 298 1985
 
ELI LILLY AND COMPANY (1)
* 4521421 Treatment of sexual dysfunction 58 1983
 
VIVUS, INC. (1)
* 5242391 Urethral insert for treatment of erectile dysfunction 88 1991
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
QUEEN'S UNIVERSITY AT KINGSTON (1)
* 2004/0092,493 Method for ameliorating male erectile dysfunction 0 2003
 
VECTURAL LIMITED (1)
* 2010/0288,276 COMPOSITIONS FOR TREATING PARKINSON'S DISEASE 11 2008
 
VECTURA DRUG DELIVERY (1)
* 2004/0204,439 Composition, device, and method for treating sexual dysfunction via inhalation 25 2003
 
OPTINOSE AS (1)
* 2010/0035,805 NON-AQUEOUS LIQUID FORMULATION FOR NASAL OR BUCCAL ADMINISTRATION 24 2007
 
NEXMED, INC. (1)
* 2014/0142,188 PROSTAGLANDIN COMPOSITIONS AND METHODS FOR THE TREATMENT OF VASOSPASM 0 2014
 
CAO GROUP, INC. (1)
* 2010/0109,179 Orally Therapeutic Plastics and Devices Formed Therefrom 2 2010
* Cited By Examiner