US Patent Application No: 2002/0165,122

Number of patents in Portfolio can not be more than 2000

Method and compositions for the treatment or amelioration of female sexual dysfunction

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provide a method of treating sexual dysfunction in a female, including the vasculogenic symptoms of delayed vaginal engorgement, diminished vaginal lubrication, pain or discomfort with intercourse (dyspareunia), diminished vaginal sensation, diminished vaginal orgasm, diminished clitoral sensation or diminished clitoral orgasm, or of combating vaginal pain by stimulating peripheral pelvic nerve release of nitric oxide (NO). The method comprises administering to a female in need of such treatment a therapeutically effective amount of a compound which acts on a mid-brain pathway to increase blood flow to the ilio-hypogastric-pudendal artery bed and stimulate the release of nitric oxide (NO) from peripheral NANC nerve cells. The preferred compound for the method of this invention is apomorphine or one of its pharmaceutically acceptable salts, esters, or pro-drugs.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
QUEEN'S UNIVERSITY AT KINGSTONKINGSTON ONTARIO112

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adams, Michael A Kingston, CA 45 409
Heaton, Jeremy P W Kingston, CA 25 287

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 4,801,587 Impotence ointment 125 1987
 
QUEEN'S UNIVERSITY AT KINGSTON (1)
* 5,770,606 Dosage forms and method for ameliorating male erectile dysfunction 46 1995
 
Pentech Pharmaceuticals, Inc. (1)
* 5,945,117 Treatment of female sexual dysfunction 32 1998
 
NORTHWESTERN UNIVERSITY (2)
* 4,543,256 (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers 18 1982
* 4,687,773 (+)-N-N-propylnorapomorphine and selective limbic activity 12 1985
 
PFIZER INC. (1)
* 5,270,323 Method of treating impotence 59 1993
 
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (1)
* 4,727,064 Pharmaceutical preparations containing cyclodextrin derivatives 288 1985
 
Eli Lilly and Company (1)
* 4,521,421 Treatment of sexual dysfunction 56 1983
 
VIVUS, INC. (1)
* 5,242,391 Urethral insert for treatment of erectile dysfunction 88 1991
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
QUEEN'S UNIVERSITY AT KINGSTON (1)
* 2004/0092,493 Method for ameliorating male erectile dysfunction 0 2003
 
VECTURAL LIMITED (1)
* 2010/0288,276 COMPOSITIONS FOR TREATING PARKINSON'S DISEASE 5 2008
 
Vectura Drug Delivery (1)
* 2004/0204,439 Composition, device, and method for treating sexual dysfunction via inhalation 17 2003
 
OPTINOSE AS (1)
* 2010/0035,805 NON-AQUEOUS LIQUID FORMULATION FOR NASAL OR BUCCAL ADMINISTRATION 20 2007
 
CAO GROUP, INC. (1)
* 2010/0109,179 Orally Therapeutic Plastics and Devices Formed Therefrom 1 2010
* Cited By Examiner