New nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria
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United States of America Patent
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Issued Date -
Nov 14, 2002
app pub date -
Feb 15, 2001
filing date -
Sep 1, 1999
priority date (Note) -
Abandoned
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Abstract
The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out: a) Fermentation of microorganisms in which at least the thrE gene is amplified (overexpressed), optionally in combination with further genes, b) Enrichment of the L-threonine in the medium or in the cells of the microorganisms, and c) Isolation of the L-threonine.
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