Optical methods and systems for rapid screening of the cervix
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United States of America Patent
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Oct 24, 2006
Grant Date -
Nov 28, 2002
app pub date -
Apr 12, 2002
filing date -
Dec 23, 1998
priority date (Note) -
Expired
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Abstract
A method and a system is provided for discriminating between healthy cervical tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and the backscatter response to illumination by white light (in the spectral range of 360 to 750 nm). Combining LIF and white light responses, as well as evaluating a spatial correlation between proximate cervical tissue sites in conjunction with a statistically significant 'distance' algorithm, such as the Mahalanobis distance between data sets, can improve the discrimination between normal and abnormal tissue. The results may be displayed in the form of a map of the cervix representing the suspected pathology.
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