Methods for use in modifying the perception of pain
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United States of America Patent
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Issued Date -
Dec 12, 2002
app pub date -
May 1, 2001
filing date -
May 1, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Use of a substance which is COX-2 selective and which can reduce prostaglandin levels of cerebrospinal fluid in a method for reducing the perception of pain in a subject is described. A preferred COX-2 selective inhibitor is nimesulide. Use of a COX-2 selective inhibitor as described has particular application in the relief of pain following surgery, especially following thoractotomy and also in the treatment of chronic post-thoracotomy pain.
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