Porous ceramic/porous polymer layered scaffolds for the repair and regeneration of tissue
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United States of America Patent
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N/A
Issued Date -
Jan 2, 2003
app pub date -
Jun 27, 2001
filing date -
Jun 27, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A composite scaffold with a porous ceramic phase and a porous polymer phase. The polymer is foamed while in solution that is infused in the pores of the ceramic to create a interphase junction of interlocked porous materials. The preferred method for foaming is by lyophilization. The scaffold may be infused or coated with a variety of bioactive materials to induce ingrowth or to release a medicament. The multi-layered porous scaffold can mimic the morphology of an injured tissue junction with a gradient morphology and cell composition, such as articular cartilage.
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