Abuse-resistant opioid dosage form
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United States of America Patent
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N/A
Issued Date -
Jan 2, 2003
app pub date -
May 10, 2002
filing date -
May 11, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention pertains to a pharmaceutical dosage form comprising an opioid agonist and one or more opioid antagonists contained in a matrix separate from the opioid agonist. The separate matrix for the opioid antagonist allows independent release rates to be achieved for the opioid and opioid antagonist(s). The antagonist(s) can be released slowly or fully contained when the tablet is taken orally. Crushing the tablet allows full release of the antagonist(s), deterring abuse. The abuse deterring antagonist(s) may be an opioid antagonist, an irritant, another appropriate antagonist(s), or a combination thereof. The invention also allows variable release of the opioid and antagonist(s).
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