US Patent Application No: 2003/0005,924

Number of patents in Portfolio can not be more than 2000

Delivery of beta-blockers through an inhalation route

ALSO PUBLISHED AS: 6740307

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Abstract

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The present invention relates to the delivery of beta-blockers through an inhalation route. Specifically, it relates to aerosols containing atenolol, pindolol, esmolol, propranolol, or metoprolol that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of atenolol, pindolol, esmolol, propranolol, or metoprolol. In a method aspect of the present invention, one of atenolol, pindolol, esmolol, propranolol, or metoprolol is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of atenolol, pindolol, esmolol, propranolol, or metoprolol, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering atenolol, pindolol, esmolol, propranolol, or metoprolol through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of atenolol, pindolol, esmolol, propranolol, or metoprolol; and, b) a device that forms a atenolol, pindolol, esmolol, propranolol, or metoprolol containing aerosol from the composition, for inhalation by the mammal.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ALEXZA PHARMACEUTICALS, INC.PALO ALTO, CA58

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rabinowitz, Joshua D Mountain View, CA 244 6758
Zaffaroni, Alejandro C Atherton, CA 197 5969

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Patent Info (Count) # Cites Year
 
ALEXZA PHARMACEUTICALS, INC. (47)
7,645,442 Rapid-heating drug delivery article and method of use 5 2003
7,585,493 Thin-film drug delivery article and method of use 5 2003
7,550,133 Respiratory drug condensation aerosols and methods of making and using them 5 2003
7,090,830 Drug condensation aerosols and kits 66 2003
7,070,761 Delivery of nonsteroidal antiinflammatory drugs through an inhalation route 43 2003
7,070,762 Delivery of analgesics through an inhalation route 55 2003
7,029,658 Delivery of antidepressants through an inhalation route 41 2003
7,018,619 Delivery of alprazolam, estazolam midazolam or triazolam through an inhalation route 57 2003
7,008,615 Delivery of anti-migraine compounds through an inhalation route 41 2003
7,005,121 Delivery of compounds for the treatment of migraine through an inhalation route 41 2003
7,115,250 Delivery of erectile dysfunction drugs through an inhalation route 41 2003
7,094,392 Delivery of antihistamines through an inhalation route 41 2003
7,078,017 Delivery of sedative-hypnotics through an inhalation route 42 2003
7,078,018 Delivery of opioids through an inhalation route 50 2003
7,078,019 Delivery of drug esters through an inhalation route 56 2003
7,078,020 Delivery of antipsychotics through an inhalation route 43 2003
7,087,216 Delivery of sedative-hypnotics through an inhalation route 41 2004
7,087,217 Delivery of nonsteroidal antiinflammatory drugs through an inhalation route 41 2004
7,070,763 Delivery of diphenhydramine through an inhalation route 41 2004
7,070,764 Delivery of analgesics through an inhalation route 55 2004
7,060,254 Delivery of antidepressants through an inhalation route 41 2004
7,045,118 Delivery of compounds for the treatment of migraine through an inhalation route 41 2004
7,052,679 Delivery of antipsychotics through an inhalation route 42 2004
7,169,378 Delivery of opioids through an inhalation route 51 2004
7,070,765 Delivery of drug esters through an inhalation route 56 2004
7,067,114 Delivery of antihistamines through an inhalation route 41 2004
7,063,830 Delivery of anti-migraine compounds through an inhalation route 41 2004
7,063,831 Delivery of erectile dysfunction drugs through an inhalation route 41 2004
7,060,255 Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route 44 2004
7,070,766 Delivery of physiologically active compounds through an inhalation route 41 2004
7,033,575 Delivery of physiologically active compounds through an inhalation route 41 2004
7,048,909 Delivery of beta-blockers through an inhalation route 41 2004
7,018,620 Delivery of beta-blockers through an inhalation route 41 2004
7,087,218 Delivery of diazepam through an inhalation route 44 2004
7,045,119 Delivery of diazepam through an inhalation route 43 2004
7,018,621 Delivery of rizatriptan or zolmitriptan through an inhalation route 43 2004
7,014,840 Delivery of sumatriptan, frovatriptan or naratriptan through an inhalation route 41 2004
7,011,819 Delivery of rizatriptan or zolmitriptan through an inhalation route 41 2004
7,005,122 Delivery of sumatriptan, frovatriptan or naratriptan through an inhalation route 41 2004
7,108,847 Delivery of muscle relaxants through an inhalation route 41 2004
7,063,832 Delivery of muscle relaxants through an inhalation route 41 2004
7,022,312 Delivery of antiemetics through an inhalation route 41 2004
7,014,841 Delivery of antiemetics through an inhalation route 41 2004
7,052,680 Delivery of compounds for the treatment of Parkinsons through an inhalation route 41 2004
7,011,820 Delivery of compounds for the treatment of Parkinsons through an inhalation route 42 2004
7,008,616 Delivery of stimulants through an inhalation route 40 2004
6,994,843 Delivery of stimulants through an inhalation route 43 2004
* Cited By Examiner