Sustained-release preparation and process for producing the same
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United States of America Patent
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-
May 22, 2007
Grant Date -
Jan 16, 2003
app pub date -
Jan 26, 2001
filing date -
Jan 27, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention is to provide a sustained release preparation comprising a drug-containing core substance and a multilayered coating layer covering the core substance, wherein all adjacent layers in the multilayered coating layer contain mutually different hydrophobic organic compound-water-soluble polymer mixtures; and, a method of producing a sustained release preparation, having a multilayered coating layer in which adjacent layers contain different hydrophobic organic compound-water-soluble polymer mixtures, which comprises spray-coating a solution containing a hydrophobic organic compound-water-soluble polymer mixture onto a drug-containing core substance, continuing to spray-coat a solution containing a different hydrophobic organic compound-water-soluble polymer mixture onto the resulting coating layer, and repeating this step.
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