Therapeutic use of rank antagonists
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United States of America Patent
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Issued Date -
Jan 23, 2003
app pub date -
May 17, 2002
filing date -
May 17, 2001
priority date (Note) -
Abandoned
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Abstract
Provided herein are methods of treating various medical conditions that require the formation of new bone by administering an effective amount of a RANK antagonist. Antagonists suitable for use in the subject methods include soluble RANK polypeptides that bind RANKL, antisense oligonucleotides that inhibit RANK activity, antibodies specific for RANK or RANKL and osteoprotegerin.
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