Apparatus and method for separation of biological contaminants

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20030019763A1





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A method of removing a biological contaminant from a mixture containing a biomolecule and the biological contaminant, the method comprising: (a) placing the biomolecule and contaminant mixture in a first solvent stream, the first solvent stream being separated from a second solvent stream by an electrophoretic membrane; (b) selecting a buffer for the first solvent stream having a required pH; (c) applying an electric potential between the two solvent streams causing movement of the biomolecule through the membrane into the second solvent stream while the biological contaminant is substantially retained in the first sample stream, or if entering the membrane, being substantially prevented from entering the second solvent stream; (d) optionally, periodically stopping and reversing the electric potential to cause movement of any biological contaminants having entered the membrane to move back into the first solvent stream, wherein substantially not causing any biomolecules that have entered the second solvent stream to re-enter first solvent stream; and (e) maintaining step (c), and optional step (d) if used, until the second solvent stream contains the desired purity of biomolecule.

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Patent Owner(s)

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International Classification(s)


Inventor Name Address # of filed Patents Total Citations
Conlan, Brendon Sydney, AU 10 15
Edgell, Tracey Ann Dee Why, AU 6 9
Lazar, May Wattle Grove, AU 6 9
Nair, Chenicheri Hariharan Old Greenwich, CT 17 104
Seabrook, Elizabeth Jean Lane Cove, AU 9 11
Turton, Thomas Norman Sydney, AU 8 11

Cited Art Landscape

Patent Info (Count) # Cites Year
* 5650055 Electrophoresis separation method and apparatus using barrier separation and polarity reversing 21 1995
* 6464851 Removal of biological contaminants 3 1999
ZymoGenetics, Inc. (1)
* 5437774 High molecular weight electrodialysis 24 1993
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
Other [Check patent profile for assignment information] (1)
8317991 Process for electrokinetic migration through liquid membranes 0 2006
* Cited By Examiner