Functional protein expression for rapid cell-free phenotyping
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United States of America Patent
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Issued Date -
Feb 27, 2003
app pub date -
Nov 27, 2001
filing date -
Nov 27, 2000
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Abstract
Disclosed herein are methods for assaying the phenotype of a bioactive molecule in the presence and absence of compounds that are known inhibitors of the phenotypable activity of the bioactive molecule. Also disclosed are methods for discovering compounds that can inhibit the phenotypable activity of a bioactive molecule. The methods and assays of the present invention are useful in developing and monitoring a chemotherapy regimen for a patient, to detect or prevent the emergence of a drug resistant phenotype.
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