Abuse-resistant controlled-release opioid dosage form
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United States of America Patent
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N/A
Issued Date -
Apr 3, 2003
app pub date -
May 10, 2002
filing date -
May 11, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level that needed to suppress the euphoric effect of the opioid, if the combination were crushed to break the controlled release properties causing the opioid and opioid antagonist to be released as a immediate release product as a single dose. The controlled release nature of the table prevents the accumulation of orally effective amounts of opioid antagonist when taken normally. The opioid antagonist is contained in a controlled-release matrix and released, over time, with the opioid.
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