Method of lyophylization to reduce solvent content and enhance product recovery
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United States of America Patent
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Issued Date -
Apr 10, 2003
app pub date -
Sep 24, 2001
filing date -
Sep 24, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention relates to an improved method for lyophilization or freeze-drying. More specifically, the present invention relates to methods for reducing the residual solvent content of a material during lyophilization or freeze-drying by the addition of a compound effective therefor, such as ascorbic acid, or a suitable derivative thereof, such as a salt or ester thereof, or mannitol.
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