Enamel matrix protein composition for treatment of systemic inflammatory response syndrome
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United States of America Patent
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Oct 27, 2009
Issued Date -
N/A
app pub date -
Sep 12, 2002
filing date -
Sep 14, 2001
priority date (Note) -
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Abstract
The present invention relates to the use of a preparation of an active enamel matrix substance, such as an amelogenin, for the manufacture of a pharmaceutical composition for modulating an immune response. The composition can be used in preventing and/or treating a condition or disease in a mammal that is characterised by said mammal presenting an imbalance in its native immune response to an internal and/or external stimuli, i.e. wherein at least a part of said mammal's immune system is stimulated non-discriminatingly, reacts hypersensitively to said immunogen, or fails to react to said stimuli. Said condition can typically either be systemic or local, such as a systemic and/or post-traumatic whole-body inflammation or an autoimmune disease.
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