Enzyme-amplified redox microarray detection process
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United States of America Patent
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app pub date -
Aug 27, 2002
filing date -
Aug 30, 2001
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Abstract
There is disclosed a process and an array for assaying for binding of target molecules to capture molecules on microarray devices, wherein the mircoarray devices contain electrodes. Specifically, there is disclosed a binding (including nucleotide hybridization) process to detect binding on a microarray wherein the microarray contains electronically addressable electrode devices. There is further disclosed an enzymatically catalyzed oxidation/reduction reaction to take place within a 'virtual flask' region of a microarray wherein the reaction is detected by current changes detected on the addressable electrode.
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