Very large scale immobilized polymers synthesis
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United States of America Patent
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Issued Date -
May 1, 2003
app pub date -
Sep 30, 2002
filing date -
Jun 7, 1989
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Abandoned
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Abstract
A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protective groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
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