Rational drug therapy device and methods
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United States of America Patent
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N/A
Issued Date -
May 1, 2003
app pub date -
Sep 24, 2002
filing date -
Sep 24, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A method and a system for treating vascular in-stent restenosis that combines two disparate drug delivery systems wherein the two drug systems act in a synergistic fashion to produce maximal therapeutic benefit at a targeted site. Controlled delivery of non-toxic, subthreshold doses of a systemic drug is combined with the localized delivery of a second drug via catheter-mediated stent placement to provide therapeutic benefit. Because each drug acts independently via distinct yet related molecular pathways, full therapeutic benefit can be designed as additives and occurs only at the targeted site.
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