Method of inducing an immune response using vaccinia virus recombinants
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United States of America Patent
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Issued Date -
May 8, 2003
app pub date -
Nov 4, 2002
filing date -
May 13, 1994
priority date (Note) -
Abandoned
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Abstract
A method of inducing expression of immune active cytokines in tumors in situ is provided wherein a vaccinia virus vector capable of inducing expression of a selected cytokine is generated and injected into a tumor so that cells of the tumor express the selected cytokine. A method of enhancing immunity in a host by administration of a vaccinia virus vector is also provided. Methods of treating cancer by administration of these vaccinia virus vectors are also provided.
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