Method of determining susceptibility to bipolar disorders
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United States of America Patent
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-
Feb 14, 2006
Grant Date -
May 8, 2003
app pub date -
Jun 14, 2002
filing date -
Jun 15, 2001
priority date (Note) -
In Force
status (Latency Note)
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Abstract
Methods and kits for determining susceptibility of a patient to bipolar disorders are described. The method comprises the steps of: (a) obtaining a sample from a patient; and (b) testing the sample for the presence of a polymorphism selected from (i) a 2 repeat allele in the variable number of tandem repeat (VNTR) region of the DRD4 gene and (ii) a 4 repeat allele in the VNTR region of the DRD4 gene, wherein the presence of the 2 repeat allele indicates that the patient is less susceptible to a bipolar disorder and the presence of the 4 repeat allele indicates that the patient is more susceptible to a bipolar disorder.
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