Interferon-Beta polynucleotide therapy for autoimmune and inflammatory diseases
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United States of America Patent
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Issued Date -
May 15, 2003
app pub date -
Mar 13, 2002
filing date -
Mar 13, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention relates to methods of treating an autoimmune disease or an inflammatory condition, and in particular multiple sclerosis, in a mammal comprising administering a therapeutically effective amount of a non-infectious, non-integrating polynucleotide construct encoding a .beta. interferon or an active fragment or variant thereof, wherein said construct is not associated with transfection-facilitating viral particles, liposomal formulations, or charged lipids.
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