Use of alpha specific antibody BIBH1 in the treatment of cancer

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United States of America Patent

APP PUB NO 20030103968A1
SERIAL NO

10121464

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Abstract

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A method of treating a patient suffering from a pathological condition characterized by expression of FAP.alpha., the method comprising administering to the patient a therapeutically effective amount of an antibody which specifically binds to FAP.alpha.. A pharmaceutical composition comprising an antibody which specifically binds to FAP.alpha., wherein the antibody is radiolabeled with .sup.131I, .sup.90Y, .sup.186Re, or .sup.188Re, and wherein the antibody has specific activity of from about 0.5 to about 15 mCi/mg, is also provided.

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Patent Owner(s)

Patent OwnerAddress
LUDWIG INSTITUTE FOR CANCER RESEARCH605 THIRD AVENUE KEW VICTORIA 3101

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amelsberg, Andree Danbury, CT 9 126
Scott, Andrew Kew, AU 31 308
Tanswell, Paul Laupheim, DE 3 106

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