Transdermal and topical administration of drugs using basic permeation enhancers
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United States of America Patent
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app pub date -
Jun 20, 2002
filing date -
Dec 16, 1999
priority date (Note) -
Abandoned
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Abstract
Methods are provided for enhancing the permeability of skin or mucosal tissue to topical or transdermal application of pharmacologically or cosmeceutically active agents. The methods entail the use of a base in order to increase the flux of the active agent through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. The permeation enhancer can be an inorganic or organic base. Compositions and transdermal systems are also described.
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