Human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10
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United States of America Patent
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Issued Date -
Jun 5, 2003
app pub date -
Jan 30, 2002
filing date -
Jan 30, 2001
priority date (Note) -
Abandoned
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Abstract
The invention provides isolated nucleic acids that encode human pp-GaNTase 10, and fragments thereof, vectors for propagating and expressing human pp-GaNTase 10 nucleic acids, host cells comprising the nucleic acids and vectors of the present invention, proteins, protein fragments, and protein fusions of the novel human pp-GaNTase 10 isoforms, and antibodies thereto. The invention further provides transgenic cells and non-human organisms comprising human pp-GaNTase 10 nucleic acids, and transgenic cells and non-human organisms with targeted disruption of the endogenous orthologue of the human pp-GaNTase 10 gene. The invention further provides pharmaceutical formulations of the nucleic acids, proteins, and antibodies of the present invention, and diagnostic, investigational, and therapeutic methods based on the human pp-GaNTase 10 nucleic acids, proteins, and antibodies of the present invention.
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