Affinity enhancement agents
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United States of America Patent
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N/A
Issued Date -
Jun 19, 2003
app pub date -
Oct 15, 2002
filing date -
Oct 15, 2001
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
This invention relates to a kit containing a multivalent, multi-specific binding protein and a carrier molecule. The binding protein has two or more binding sites where at least one binding site binds with a hapten moiety and at least one site binds with a target antigen. The carrier molecule contains a linking molecule that bears a diagnostic agent and/or a therapeutic agent and two or more haptens. The present invention further relates to bispecific diabodies that bind with hapten moieties and target antigens and to recombinant vectors useful for the expression of these-functional diabodies in a microbial host.
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