Substituted piperazine derivatives as mtp inhibitors
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United States of America Patent
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Issued Date -
Jun 19, 2003
app pub date -
Oct 8, 2002
filing date -
Dec 27, 1999
priority date (Note) -
Abandoned
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Abstract
The present invention relates to substituted piperazine derivatives of general formula 1 wherein R.sub.a to R.sub.c, Y.sub.a, Y.sub.b, X and n are defined as in claim 1, the isomers and salts thereof, particularly the physiologically acceptable salts thereof, which are valuable inhibitors of the microsomal triglyceride-transfer protein (MTP), medicaments containing these compounds and their use, as well as the preparation thereof.
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