Method for enhancing the presentation of exogenous antigen by human antigen-presenting cells and opsonized micro particle complexes for applying this method
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United States of America Patent
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Issued Date -
Jul 17, 2003
app pub date -
Nov 4, 2002
filing date -
Jan 21, 2000
priority date (Note) -
Abandoned
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Abstract
The invention relates to an opsonized micro-particle complex comprising: a micro-particular vector encapsulating at least one antigen, and at least one antibody or fragment thereof, with said antibody being a human or humanized antibody or an antibody binding to human FcR with substantially the same affinity and avidity as the ones of a human antibody and with said antibody or fragment thereof having the carboxy terminal end of its Fc portion external with respect to the opsonized micro particle complex.
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