Dynamic sequencing by hybridization
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United States of America Patent
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Issued Date -
Jul 24, 2003
app pub date -
May 29, 2002
filing date -
Nov 29, 1999
priority date (Note) -
Abandoned
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Abstract
The invention relates to a method for sequencing nucleic acids using carrier chips that contain polymer probes, which are constructed of nucleotides and/or nucleotide analogs and which permit a specific binding with nucleic acids present in the sample. The method is dynamically carried out in a number of cycles, whereby the sequence information obtained from a preceding cycle is used for modifying carrier-bound probes in the subsequent cycle.
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