Use of inhibition of a gas6 function or of a gas6 receptor for preventing and treating a cardiovascular disease

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United States of America Patent

APP PUB NO 20030144237A1
SERIAL NO

10257173

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An antagonist to the activator of the Rse and Mer receptor protein tyrosine kinases, encoded by growth arrest-specific gene 6 (gas6), is found to be useful in a method of treating an insulin-resistant disorder such as diabetes. More particularly, a method for treating an insulin-resistant disorder is provided which comprises administering to a mammal in need of such treatment an effective amount of a composition comprising a gas6 antagonist. A hypoglycemic agent may be co-administered with the gas6 antagonist.

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Patent Owner(s)

Patent OwnerAddress
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE (VIB)RIJVISSCHESTRAAT 120 ZWIJNAARDE B-905
D COLLEN RESEARCH FOUNDATION VZWK U LEUVEN HERESTRAAT 49

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Angelillo-Scherrer, Anne Etoy, CH 6 2
Carmeliet, Peter Oud-Heverlee, BE 50 274
Collen, Desire London, GB 28 134

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