Peptide production

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United States of America Patent

SERIAL NO

10253890

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Abstract

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A method of producing a substance comprising a peptide, involves incorporating a DNA sequence coding for the peptide into a gene of a mammal (such as a sheep) coding for a milk whey protein in such a way that the DNA sequence is expressed in the mammary gland of the adult female mammal. The substance may be an (optionally modified) protein such as a blood coagulation factor. The DNA sequence is preferably inserted into the first exon of a gene coding for a whey protein such as beta-lactoglobulin. The substance will generally be recovered from milk of the female mammal, but may (for example if it is an enzyme) be used in situ.

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Patent Owner(s)

Patent OwnerAddress
PHARMING INTELLECTUAL PROPERTY BVP O BOX 451 AL LEIDEN 2300

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clark, Anthony John Edinburgh, GB 31 327
Lathe, Richard Strasbourg, FR 19 180

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