Methods for determining whether a compound alters the amount of at least one αβ (X-41) peptide and the amount of either total αβ or at least one αβ (X-40) peptide produced by a non-human mammal
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United States of America Patent
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Aug 9, 2011
Grant Date -
Aug 7, 2003
app pub date -
Dec 30, 2002
filing date -
Jul 10, 1992
priority date (Note) -
Expired
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Abstract
This invention provides methods of screening compounds for their ability to alter the production of Aβ(x≧41) alone or in combination with Aβ(x≦40). The methods involve administering compounds to cells, specifically measuring the amounts of Aβ(x≦40) and Aβ(x≧41) produced by the cells, and comparing these amounts to that produced by the cells without administration of the compounds.
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