Intravascular delivery of therapeutic and imaging agents to stressed and apoptotic cells using annexin V as a targeting vector

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United States of America Patent

APP PUB NO 20030152513A1
SERIAL NO

10238026

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Abstract

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The present invention relies on the affinity of stressed or apoptotic cells for exogenously administered annexin V to create a multi-functional molecular probe that can be simultaneously used for imaging (localization of unstable plaque within the body) and therapy (treatment of unstable plaque).

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Patent Owner(s)

Patent OwnerAddress
IMETRX INC801 HERMOSA MENLO PARK CA 94025

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blankenberg, Francis G Menlo Park, CA 11 80
Ghazarossian, Vartan Menlo Park, CA 32 1326
Narula, Jagat Seattle, WA 8 72
Strauss, H William Redwood City, CA 20 732

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