Methods for identifying compounds that modulate disorders related to nitric oxide/ cGMP-dependent protein kinase signaling
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United States of America Patent
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Issued Date -
Sep 4, 2003
app pub date -
Dec 15, 2000
filing date -
Dec 15, 2000
priority date (Note) -
Abandoned
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Abstract
The invention provides a method of identifying a compound that modulates a disease associated with a nitric oxide/cGMP-dependent protein kinase network in a mammal. The method consists of (a) administering a test compound to an invertebrate; and (b) measuring a foraging behavior of the invertebrate, wherein a compound that modulates the foraging behavior of the invertebrate is characterized as a compound that modulates a disease associated with a nitric oxide/cGMP-dependent protein kinase network in a mammal.
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