SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
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United States of America Patent
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Aug 24, 2010
Grant Date -
Sep 4, 2003
app pub date -
Oct 31, 2002
filing date -
Oct 31, 2001
priority date (Note) -
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Abstract
The present invention identifies the semaphorin polypeptide SEMA3B as a tumor suppressor. This molecule can inhibit tumor growth and induce apoptosis of tumor cells when produced internally in a cancer cell via gene transfer, or when applied extracellularly. These observations permit new methods for treatment and diagnosis of cancer.
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