Macromolecule detection
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Issued Date -
Sep 18, 2003
app pub date -
May 23, 2003
filing date -
Apr 3, 2000
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A method is provided of labelling a protein, which method comprises the steps of (a) treating the protein with a protecting agent so as to block epsilon amino acid groups present on lysines residues of the protein, (b) cleaving the protein into a peptide mixture; and (c) treating the peptide mixture with a labelled agent which binds to N-terminal amino acids of the peptides. The method may be used in differential expression detection methods for determining differences in protein expression.
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