Hetrocyclic compounds that are inhibitors of the enzyme DPP-IV
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United States of America Patent
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Issued Date -
Oct 23, 2003
app pub date -
Jan 28, 2003
filing date -
Sep 19, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity. The present inhibitors are novel purine derivatives, attached at position 8 of the purine skeleton to a diamine.
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