Genetic analysis of peyer's patches and M cells and methods and compositions targeting peyer's patches and M cell receptors
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United States of America Patent
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Issued Date -
Nov 13, 2003
app pub date -
Apr 4, 2002
filing date -
Apr 4, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Methods of increasing of or decreasing the levels of a protein in a PP cell; methods of increasing antigen, vaccine, DNA vaccine delivery to M cells, use of human serum albumin and other transport enhancing proteins to enhance oral drug delivery; use of calreticulin to enhance oral antigen delivery, use of other cell surface proteins, receptors, and transporters to enhance delivery to M cells of antigens or vaccine delivery vehicles, use of other cytoplasmic proteins to regulate intracellular trafficking and delivery to mucosal immune sampling and processing systems.
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