Compositions and methods for gene therapy
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United States of America Patent
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Issued Date -
Nov 13, 2003
app pub date -
Dec 12, 2002
filing date -
Mar 23, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) physically linked to a transfection agent for use in embolization gene therapy. The present invention further relates to methods of embolization gene therapy, particularly for the treatment of angiogenic and non-angiogenic-dependent diseases, using the injectable compositions.
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