Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
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United States of America Patent
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Issued Date -
Nov 20, 2003
app pub date -
Mar 12, 2003
filing date -
Mar 12, 2002
priority date (Note) -
Abandoned
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Abstract
This invention provides device for co-culturing at least two different cell types in a two-dimensional configuration, methods of patterning at least two different cell types in a two-dimensional co-culture configuration, and uses of these devices and methods for analyzing an effect of candidate compound on such cellular cocultures. Also provided is a transmigration and extravasation device. Assay devices for analyzing the absorption, permeability, metabolism and/or toxicity of a candidate compound by a cell are provided. A microfluidic network, which is adaptable for integration with a device for coculturing is provided.
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