Microfluidic separation devices and methods

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United States of America Patent

SERIAL NO

10219597

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Abstract

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A pressure-driven microfluidic device for separating chemical or biological species from a sample provides on-column sample injection from a sample loading segment, with mobile phase solvent supplied to both the separation column and the sample loading segment to promote high-quality separation. Multiple separation channels each having an associated sample loading segment may be provided in a single device, with a first mobile phase solvent being supplied to an upstream portion of each separation channel via a first channel network and a second mobile phase solvent being supplied to each sample loading segment via a second channel network. Methods for operating pressure-driven microfluidic separation devices include the steps of supplying a sample to a sample loading segment and flowing mobile phase solvent an associated separation channel upstream of the sample loading region.

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Patent Owner(s)

Patent OwnerAddress
NANOSTREAM INC580 SIERRA MADRE VILLA PASADENA CA 91107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gamble, Ronald C Altadena, CA 35 1759
Karp, Christoph D Pasadena, CA 37 3080

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