Optimized promoter constructs

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United States of America Patent

APP PUB NO 20030224477A1
SERIAL NO

10160851

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention features constructs and related methods for expression of products in mammalian cells, e.g., human cells. Constructs include a human .gamma.-actin, .beta.-actin, fibronectin, YY1, or .beta.-tubulin promoter region operably linked to a heterologous nucleic acid sequence.

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Patent Owner(s)

Patent OwnerAddress
TRANSKARYOTIC THERAPIES INC195 ALBANY STREET CAMBRIDGE MA 02139 MA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Concino, Michael F Bolton, MA 28 484
Heartlein, Michael W Boxborough, MA 46 1004
Kempinski, Heidi Charlton, MA 3 20
Lamsa, Justin Chace Westminster, MA 1 10
Selden, Richard F Wellesley, MA 83 1752
Treco, Douglas A Arlington, MA 61 968

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