Sequential drug delivery systems
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United States of America Patent
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app pub date -
Jul 18, 2003
filing date -
Jul 10, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention relates to methods and composition for improving absorption and dissolution of active ingredients of drugs. The invention provides a method of administration of an active ingredient to a mammal through a transmucosal route that includes delivering the active ingredient to a desired site in a body of the mammal, and, sequentially, at the desired site, promoting dissolution and absorption of the active ingredient. In a preferred embodiment, the pH of the localized environment of the active ingredient is sequentially modified to promote dissolution and absorption.
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