siRNA expression system and method for producing functional gene knock-down cell using the system
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United States of America Patent
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Issued Date -
Jan 1, 2004
app pub date -
Nov 27, 2002
filing date -
Nov 28, 2001
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Abandoned
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Abstract
The in vivo siRNA expression system according to this invention is a system that intracellularly expresses small interfering (si) RNAs and comprises antisense and sense code DNAs coding for antisense and sense RNAs targeting any region of a target gene mRNA and one or more promoters that function to express the antisense and sense RNAs from the antisense and sense code DNAs, respectively.
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