Targeted delivery of genes encoding interferon
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United States of America Patent
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Issued Date -
Jan 1, 2004
app pub date -
Nov 26, 2001
filing date -
Mar 14, 1996
priority date (Note) -
Abandoned
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Abstract
A molecular complex comprising a gene encoding interferon releasably linked to a conjugate of a nucleic acid binding agent and a ligand which binds to a component on the surface of a cell. In a preferred embodiment, the gene encodes human IFN-.alpha., IFN-.beta., or IFN-.gamma.. The complex can be used to obtain targeted expression of interferon in selected cells either in vivo or in vitro.
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