Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery
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United States of America Patent
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-
Mar 9, 2004
Grant Date -
Jan 1, 2004
app pub date -
Nov 30, 2001
filing date -
Jun 20, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method including positioning a catheter at a location in a blood vessel; imaging a thickness of a portion of a wall of the blood vessel at the location; identifying a treatment site; advancing a needle a distance into the wall of the blood vessel to the treatment site; and introducing a treatment agent through the needle to the treatment site. A composition including an inflammation-inducing agent and a carrier in the form of microspheres having a particle size suitable for transvascular delivery. A composition including a therapeutic angiogenesis promoter in a carrier and an opsonin-inhibitor coupled to the carrier. An apparatus for delivery of a therapeutic angiogenesis promoter.
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