Implantable devices for the controlled release of cytotoxic agents
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United States of America Patent
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Issued Date -
Jan 22, 2004
app pub date -
Jul 16, 2002
filing date -
Jul 16, 2002
priority date (Note) -
Abandoned
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Abstract
An implantable device that includes at least one sealed chamber containing any of a variety of therapeutic or cytotoxic agents is described. The device is implanted into the patient at one or more sited requiring treatment, e.g., at several sites within a tumor. Once the device is implanted in the patient, the chamber retains its contents until a bioresorbable element of the chamber (e.g., a seal) dissolves, creating an opening through which the agent migrates out of the chamber and enters the body. The bioresorbable element can be simply a plug seal in a plastic or metal chamber. Alternatively, all or part of the chamber itself can be formed of a bioresorbable material. The agent can be chemical or biological.
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