Molecular differences between species of the M. tuberculosis complex
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United States of America Patent
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Issued Date -
Jan 29, 2004
app pub date -
Mar 14, 2003
filing date -
Aug 25, 1998
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Abandoned
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Abstract
Specific genetic deletion are identified in mycobacteria isolates, including variations in the M. tuberculosis genome sequence between isolates, and numerous deletion present in BCG as compared to M. tbThe genetic markers can be used for diagnosis of M. tb. infection. One or more antigens provided from the genetic markers can be used in diagnostic assays, e.g. a serological assay.
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