US Patent Application No: 2004/0023,313

Number of patents in Portfolio can not be more than 2000

Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors

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Abstract

Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MEDAREX, INC.PRINCETON, NJ137

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boyle, William J Fallbrook, CA 115 3006
Elliott, Robin L Newbury Park, CA 7 20
Huang, Haichun Fremont, CA 66 106
Martin, Frank San Clemente, CA 29 145
Medlock, Eugene Westlake Village, CA 22 66
Sullivan, John J 270 Morgan St., South Hadley, MA 01075 11 53

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
IMMUNEX CORPORATION (5)
7,411,050 Monoclonal blocking antibody to human RANKL 9 2004
7,932,375 Kits for detecting rank nucleic acids 3 2007
7,790,684 Method of inhibiting osteoclast activity 0 2008
7,744,886 Methods for interfering with rank signaling 5 2008
8,377,690 Cells and methods for producing blocking antibodies to human RANKL 0 2010
 
DAIICHI SANKYO COMPANY, LIMITED (3)
7,527,790 Methods of reducing bone absorption comprising administering an antibody that binds OBM 6 2002
7,192,718 Methods for identifying a substance which specifically binds to an osteoclastogenesis inhibitory factor-binding molecule and modulates the biological activity thereof 6 2003
7,449,185 Antibodies to OCIF-binding molecules 6 2004
 
AMGEN INC. (2)
7,807,795 Antibodies to osteoprotegerin binding proteins 1 1998
7,923,008 Methods for decreasing osteoclast formation or bone resorption using an antibody to osteoprotegerin binding protein 3 2006
 
ALETHIA BIOTHERAPEUTICS INC. (1)
8,431,126 Antibodies that bind polypeptides involved in the process of bone remodeling 0 2012
 
TRACON PHARMACEUTICALS, INC. (1)
8,221,753 Endoglin antibodies 0 2010