Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof

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United States of America Patent

SERIAL NO

10446628

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Abstract

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The present invention provides peptides having an amino acid sequence that is the amino acid sequence of a human bactericidal/permeability-increasin-g protein (BPI) functional domain or a subsequence thereof, and variants of the sequence or subsequence thereof, having at least one of the BPI biological activities, such as heparin binding, heparin neutralization, LPS binding, LPS neutralization or bactericidal activity. The invention provides peptides and pharmaceutical compositions of such peptides for a variety of therapeutic uses.

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Patent Owner(s)

Patent OwnerAddress
XOMA CORPORATION2910 7TH STREET BERKELEY CALIFORNIA 94710 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Little, Roger G II Benicia, CA 5 8

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