Solvates and polymorphs of ritonavir and methods of making and using the same
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United States of America Patent
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Apr 17, 2007
Grant Date -
Feb 5, 2004
app pub date -
May 1, 2003
filing date -
May 3, 2002
priority date (Note) -
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Abstract
Novel solvates and crystal polymorphs of Ritonavir are disclosed, as well as methods of making them. Specific solvates of the compound include a formamide solvate and a partially desolvated solvate. Also disclosed are methods of making previously known forms of Ritonavir. Methods of using the novel forms of Ritonavir for the treatment of diseases, such as HIV-infection, are disclosed, as are pharmaceutical compositions and unit dosage forms comprising the novel forms of Ritonavir.
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